Trusted Resources: Evidence & Education
Scientific literature and patient education texts
Vitamin D and Graves’ Disease: A Meta-Analysis Update
source: Nutrients
year: 2015
authors: Xu MY, Cao B, Yin J, Wang DF, Chen KL, Lu QB
summary/abstract:The association between vitamin D levels and Graves’ disease is not well studied. This update review aims to further analyze the relationship in order to provide an actual view of estimating the risk. We searched for the publications on vitamin D and Graves’ disease in English or Chinese on PubMed, EMBASE, Chinese National Knowledge Infrastructure, China Biology Medical and Wanfang databases. The standardized mean difference (SMD) and 95% confidence interval (CI) were calculated for the vitamin D levels. Pooled odds ratio (OR) and 95% CI were calculated for vitamin D deficiency. We also performed sensitivity analysis and meta-regression. Combining effect sizes from 26 studies for Graves’ disease as an outcome found a pooled effect of SMD = −0.77 (95% CI: −1.12, −0.42; p < 0.001) favoring the low vitamin D level by the random effect analysis. The meta-regression found assay method had the definite influence on heterogeneity (p = 0.048). The patients with Graves’ disease were more likely to be deficient in vitamin D compared to the controls (OR = 2.24, 95% CI: 1.31, 3.81) with a high heterogeneity (I2 = 84.1%, p < 0.001). We further confirmed that low vitamin D status may increase the risk of Graves’ disease.
organization: Aerospace Center Hospital, China; Peking University, ChinaDOI: 10.3390/nu7053813
read more
myBinderRelated Content
-
The Brazilian Consensus for the Diagnosis and Treatment of Hyperthyroidism: Recommendations by the Thyroid Departmen...Introduction: Hyperthyroidism is charac...
-
In Young Patients With Turner or Down syndrome, Graves’ Disease Presentation is Often Preceded by Hashimoto...Background: It is known that, in the ge...
-
Graves’ Disease in Children: Thyroid-Stimulating Hormone Receptor Antibodies as Remission MarkersObjective: To evaluate clinical and bio...
-
Diagnosing Graves’ Disease in ChildrenGraves' disease is an autoimmune conditi...
-
Thyroid Eye Disease – A Summary for PatientsThyroid eye disease (TED) is an inflamma...
-
Dr. Scott Rivkees – “What to Expect and How To Deal with the Stress of a Child with Graves’ Diseas...https://www.youtube.com/watch?v=oC_yM7Lk...
-
Avoiding Grave Cardiac Outcomes in an Athlete with Grave’s DiseaseHistory: A 20-yr male college football ...
To improve your experience on this site, we use cookies. This includes cookies essential for the basic functioning of our website, cookies for analytics purposes, and cookies enabling us to personalize site content. By clicking on 'Accept' or any content on this site, you agree that cookies can be placed. You may adjust your browser's cookie settings to suit your preferences. More Information
The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.
Powered by
Google