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The History of Levothyroxine – The Most Prescribed Drug in the United States With Dr. James V. Hennessey from Harvard University
In this interview, Dr. Hennessey describes the history, refinements, implementation, physiology, and clinical outcomes achieved over the past several centuries of thyroid hormone replacement strategies.
Topics discussed in this episode include:
• The history of levothyroxin
• Chinese using thyroid hormone to treat cretinism in the 6th century
• What is cretinism?
• Dangers of hypothyroidism during pregnancy
• Prescribed 3-step process when hypothyroidism is treated when pregnant
• The history of sheep thyroid as a treatment
• In the 1920’s thyroid hormone was synthesized
• T3 was synthesized in the 1950’s
• When to take thyroid medication, morning or night?

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