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An early and intensive control of hyperthyroidism in Graves’ disease is associated with reduced mortality and cardiovascular risk independent of the method of treatment, according to findings from a linked-record cohort study.
“We have shown that patients with Graves’ disease have an increased risk of mortality and cardiovascular disease, which can be reduced by effective and early control of hyperthyroidism,” Onyebuchi Okosieme, MD, FRCP, a consultant endocrinologist with Cwm Taf University Health Board in Wales and an honorary senior research fellow at Cardiff University, United Kingdom, told Endocrine Today. “Patients successfully treated with radioactive iodine in the first year of diagnosis had reduced long-term risk for mortality and major adverse cardiovascular events compared with those treated with antithyroid drugs alone or with those treated with radioiodine without control of hyperthyroidism.”
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