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Supplements, Cancer Therapies, Endocrine-Disrupting Chemicals can Alter Thyroid Function
Medications, supplements, excessive iodine intake and other exogenous substances including endocrine-disrupting chemicals can influence multiple thyroid effects that clinicians should recognize, including thyroid dysfunction and altered thyroxine absorption, according to a speaker at the AACE Annual Scientific and Clinical Congress.
Several commonly used drugs and popular over-the-counter supplements, as well as newer cancer treatments such as immune checkpoint inhibitors, can interfere with thyroid function test measurement and thyroid hormone metabolism, disrupt the thyroid axis and even trigger autoimmune thyroid disease, Gregory A. Brent, MD, Professor of medicine and physiology in the Division of Endocrinology at the David Geffen School of Medicine at UCLA, said. Popular OTC dietary supplements such as biotin, a water-soluble vitamin often marketed for hair and nail growth, can interfere with a range of thyroid assays that rely on the interaction of biotin and streptavidin, Brent said.
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