Advances in the Pharmacological Treatment of Graves' Orbitopathy | oneGRAVESvoice

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Scientific Articles

Advances in the Pharmacological Treatment of Graves’ Orbitopathy

key information

source: Expert Review of Clinical Pharmacology

year: 2016

authors: Ruchała M, Sawicka-Gutaj N


Graves’ orbitopathy has a deteriorating effect on patients’ appearance and vision, thus significantly decreases their quality of life. A multidisciplinary team of endocrinologists, ophthalmologists, head and neck surgeons, nuclear medicine physicians, radiologists, and psychologists should constitute a standard health care team for those patients. It is vital that the therapy is based on an individual approach, with patients being well informed and involved in the decision-making process.

Generally, traditional therapies include immunosuppression with steroids, orbital irradiation and surgical decompression. Novel treatment modalities include: biological agents, somatostatin analogs, antioxidants, methotrexate. Better insight into pathogenesis of Graves’ orbitopathy is the only chance for targeted therapy development.

organization: Poznan University of Medical Sciences, Poland

DOI: 10.1586/17512433.2016.1165606