source: Expert Review of Clinical Pharmacology
authors: Ruchała M, Sawicka-Gutaj N summary/abstract:
Graves’ orbitopathy has a deteriorating effect on patients’ appearance and vision, thus significantly decreases their quality of life. A multidisciplinary team of endocrinologists, ophthalmologists, head and neck surgeons, nuclear medicine physicians, radiologists, and psychologists should constitute a standard health care team for those patients. It is vital that the therapy is based on an individual approach, with patients being well informed and involved in the decision-making process.
Generally, traditional therapies include immunosuppression with steroids, orbital irradiation and surgical decompression. Novel treatment modalities include: biological agents, somatostatin analogs, antioxidants, methotrexate. Better insight into pathogenesis of Graves’ orbitopathy is the only chance for targeted therapy development.organization:
Poznan University of Medical Sciences, Poland DOI: