Randomized Trial of a Short Course of Preoperative Potassium Iodide in Patients Undergoing Thyroidectomy for Graves' Disease | oneGRAVESvoice

welcome to oneGRAVESvoice

- a positively charged Graves' disease and thyroid eye disease community.
  • join today!
Scientific Articles

Randomized Trial of a Short Course of Preoperative Potassium Iodide in Patients Undergoing Thyroidectomy for Graves’ Disease

key information

source: American Journal of Surgery

year: 2017

authors: Whalen G, Sullivan M, Maranda L, Quinlan R, Larkin A

summary/abstract:

Background:
A short course of potassium iodide (SSKI) has been traditionally used to prepare patients with Graves’ disease for thyroidectomy. The rationale for this treatment has evolved over time; from control of hyperthyroidism to facilitating surgery by making the gland less friable and bloody.

Methods:
Randomized trial of preoperative SSKI vs no SSKI to test whether that is true.

Results:
Mean estimated blood loss in the SSKI group (62 mL) was less than in the control group (162 mL) as was the median estimated blood loss (50 vs 140 mL). Mean (142 vs 162 minutes) and median (138 vs 150 minutes) operative times were also less in the SSKI arm. Subjective difficulty of operation was similar. Multivariable comparisons of groups with analysis of covariance showed the SSKI group suffered a mean blood loss 35% of the no treatment group (P = .036), the 9.2% decrease in Operating Room (OR) time between the SSKI group and the no treatment group was not statistically different (P = .464).

Conclusions:
SSKI given before operation in patients with Graves’ disease reduces blood loss during thyroidectomy.

organization: UMass Memorial Health Center, USA; Department of Quantitative Health Sciences, USA

DOI: 10.1016/j.amjsurg.2016.07.015

Font Resize

To improve your experience on this site, we use cookies. This includes cookies essential for the basic functioning of our website, cookies for analytics purposes, and cookies enabling us to personalize site content. By clicking on 'Accept' or any content on this site, you agree that cookies can be placed. You may adjust your browser's cookie settings to suit your preferences.
More information

The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.

Close