Alternative Thyroid Hormone-Replacement Options in Patients With Hypothyroidism | oneGRAVESvoice

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Symptoms Strongly Drive the Consideration of Alternative Thyroid Hormone-Replacement Options in Patients With Hypothyroidism

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source: Clinical Thyroidology

year: 2019


The standard treatment for hypothyroidism is synthetic levothyroxine (L-T4) due to its’ long half-life and that it most closely mimics the thyroid production of T4. However, many doctors that treat thyroid conditions have patients who are dissatisfied with their treatment and who request combination therapy with either desiccated thyroid extract or combination therapy with liothyronine (L-T3).

The American Thyroid Association published its treatment guidelines for adults with hypothyroidism in 2014. These guidelines were devised after careful review of current scientific knowledge, and the committee concluded that there was not enough evidence to recommend using liothyronine (L-T3) on a routine basis. In 2017, the results of a patient survey showed a low level of satisfaction with their treatment and a greater satisfaction among patients taking desiccated thyroid extract. However, because of how this survey was distributed, it is possible that patients who had strong feelings about their therapy were most likely to respond and this could have very much influenced results reported.



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