Thyroidectomy for Graves' Disease in Children: Indications and Complications | oneGRAVESvoice

welcome to oneGRAVESvoice

- a positively charged Graves' disease and thyroid eye disease community.
  • join today!
Scientific Articles

Thyroidectomy for Graves’ Disease in Children: Indications and Complications

key information

source: Journal of Pediatric Surgery

year: 2016

authors: Elfenbein DM, Katz M, Schneider DF, Chen H, Sippel RS


The utilization of thyroidectomy for Graves’ disease remains controversial; we aim to evaluate the indications for and complications of thyroidectomy for Graves’ in children.

A retrospective analysis was performed on all Graves’ patients who underwent thyroidectomy from 2009 to 2013 at a high volume academic center. Pediatric patients were <18years old, and a comparative analysis of indications for surgery and complications was performed.

167 patients underwent thyroidectomy: 31 pediatric patients and 136 adults. Failure of antithyroid medications was the indication for surgery in 55% of the children vs 36% of adults (p=0.05). Mean duration of medications prior to surgery was similar. No children had failed RAI therapy prior to surgery, but 12.5% of the adult population had (p=0.04). Surgical outcomes were similar.

Clinicians may be more likely to refer children who fail medical treatment to surgery over RAI. Thyroidectomy at a high volume hospital should be discussed as a treatment option for children with Graves’.

organization: University of Wisconsin, USA

DOI: 10.1016/j.jpedsurg.2016.03.009

full text source