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Terry Jay Smith, MD

Healthcare Professional
Professor
Department of Ophthalmology and Visual Sciences
University of Michigan Kellogg Eye Center
Elevator B Floor 3
1000 Wall St
Ann Arbor, Michigan, United States

Dr. Terry J. Smith, the Frederick G.L. Huetwell Professor in Ophthalmology and Visual Sciences at the University of Michigan, is an internationally-known endocrinologist who has studied Graves’ disease, its eye manifestations, and related autoimmune disease for over 20 years. His areas of practice are Graves’ disease, thyroid-associated ophthalmopathy and metabolic diseases.

Dr. Smith received his medical degree from the University of Missouri School of Medicine and completed his residency at the University of Illinois in Chicago and Sinai Hospital in Baltimore. He has completed fellowships in biophysics at the University of California School of Medicine, San Francisco, in molecular biochemistry at Columbia University in New York, and clinical endocrinology at the Pritzker School of Medicine, University of Chicago.

Dr. Smith is the author of over 150 articles and book chapters, and has been awarded five patents for his research discoveries. He has been elected to the Orbit Society, as chief scientific officer for the National Graves’ Foundation, and serves as reviewer for numerous scientific journals.

Dr. Smith’s research areas are autoimmune thyroid disease, extracellular matrix, cell signaling, gene expression, ecosanoids, inflammation and cytokine action. His laboratory group is interested in understanding and developing new treatments for Graves’ disease (GD) or thyroid-associated ophthalmopathy (TAO).

Representative Publications:

The Insulin-Like Growth Factor-I Receptor and its Role in Thyroid-Associated Ophthalmopathy

Cytokines, Graves’ Disease, and Thyroid-Associated Ophthalmopathy

Biologic Therapeutics in Thyroid-Associated Ophthalmopathy: Translating Disease Mechanism into Therapy

Evidence For An Association Between Thyroid-Stimulating Hormone and Insulin-Like Growth Factor 1 Receptors: A Tale of two Antigens Implicated in Graves’ Disease

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