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Gut Microbes May Play Role in Graves ’ Disease Diagnosis, Thyroid Autoimmunity
The abundance and diversity of intestinal microbiota are reduced in adults with Graves’ disease, and Lactobacillus may be one of the pivotal factors activating autoimmune response, according to data published in Thyroid. In an analysis of fecal samples collected from participants with untreated Graves’ disease as well as healthy volunteers, researchers also found that nine significant genera are “promising” as microbial markers to distinguish those with Graves’ disease from healthy controls.
“The characteristics of the composition, abundance and diversity of the gut microbiota identified in this study may be beneficial to provide new insights into the pathogenesis of Graves’ disease, as well as new ideas for microecological therapies, such as probiotics or prebiotics for Graves’ disease”, Dan Li, MD, PhD, vice director of the department of nuclear medicine department, associate chief physician and associate professor at Shanghai Tenth People’s Hospital and Tongji University School of Medicine, China, told Healio.
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